Das Medizinportal


Schwerpunkt: Glaskörper + Netzhaut


Idiopathische und traumatische Makulaforamina: Welche Unterschiede sind relevant für das tägliche Patientenmanagement?

Ricarda G. Schumann

Seiten 10–13

  1. Bartz-Schmidt K-U et al (2013) Current Statement of the German Ophthalmological Society, the Retina Society and the Professional Association of German Ophthalmologists for therapeutic intravitreal application of Ocriplasmin (JETREA ®) in ophthalmology (May 2013). Klin Monbl Augenheilkd 230: 629-634
  2. Chen H, Chen W, Zheng K, et al. Prediction of spontaneous closure of traumatic macular hole with spectral domain optical coherence tomography. Sci Rep 2015; 21;5:12343
  3. Duker JS, Moshfeghi AA (2013) Ocriplasmin: a medical or surgical therapy? Retina 33: 2001-2002
  4. Duker JS, Kaiser PK, Binder S, et al. The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole. Ophthalmology 2013;20(12):2611-2619
  5. Fiorentzis M, Seitz B, Viestenz A. Traumatic macular hole with central retinal detachment and choroidal rupture with ora serrata dialysis. Ophthalmologe 2015; 112(8):682-685Ng Ch et al (2011) Prevalence and risk factors for epiretinal membranes in a multi-ethnic United States population. Ophthalmology 118: 694-699
  6. Huang J, Liu X, Wu Z, Sadda S. Comparison of full-thickness traumatic macular holes and idiopathic macular holes by optical coherence tomography. Graefes Arch Clin Exp Res 2010; 248(8):1071-1075
  7. Liu W, Grzybowski A. Current management of traumatic macular holes. J Opthalmlol 2017; 2017:1748135 
  8. Miller JB, Yonekava Y, Eliott D, et al. Long-term Follow-up and Outcomes in Traumatic Macular Holes. Am J Ophthalmol 2015; 160(6):1255-1258.e1 
  9. Schumann RG et al (2010) Sequential epiretinal membrane removal with internal limiting membrane peeling in brilliant blue G-assisted macular surgery. Br J Ophthalmol 94: 1369-72
  10. Sebag J (2004) Anomalous posterior vitreous detachment: a unifying concept in vitreo-retinal disease. Graefes Arch Clin Exp 242: 690-698 
  11. Sebag J et al (2009) Vitreopapillary adhesion in macular diseases. Trans Am Ophthalmol Soc 107: 35-46
  12. Stalmans P et al (2013) OCT-based interpretation of the vitreomacular interface and indications for pharmacologic vitreolysis. Retina 33: 2003-2011


Aktuelle europäische EURETINA-Leitlinie zum DMÖ: Einsatz von intravitrealen Steroiden und Anti-VEG- Präparaten

Ramin Khoramnia

Seiten 14–15

  1. Schmidt U et al., Ophthalmologica 2017; 237: 185-222
  2. Gillies MC et al., Ophthalmology 2014; 121: 2473-2481
  3. Busch C et al., Acta Diabetologica 2018; 55: 789-796
  4. Campochiaro PA et al., Ophthalmology 2012; 119: 2125-2132
  5. Augustin AJ et al., Investigative Ophthalmology & Visual Science 2017; 5: 928
  6. Kane FE et al., Expert Opin Drug Deliv 2008; 5: 1039-1046
  7. Khoramnia R et al., ARVO-Kongress 2019, Poster B0150
  8. Koch FH et al., ARVO-Kongress 2019, Poster B0153


Augenprothetische Versorgung – alles nur reine Kosmetik und nur eine Sache der Okularisten?

Alexander C. Rokohl; Marc Trester; Joel M. Mor; Niklas Loreck; Konrad R. Koch; Ludwig M. Heindl

Seiten 18–22

  1. de Gottrau P, Holbach LM, Naumann GO. Clinicopathological review of 1146 enucleations (1980-90). Br J Ophthalmol. 1994;78(4):260-5.
  2. Koch KR, Trester W, Muller-Uri N, Trester M, Cursiefen C, Heindl LM. [Ocular prosthetics. Fitting, daily use and complications]. Ophthalmologe. 2016;113(2):133-42.
  3. Rokohl AC, Koch KR, Trester M, Trester W, Pine KR, Heindl LM. Concerns of Anophthalmic Patients Wearing Cryolite Glass Prosthetic Eyes. Ophthal Plast Reconstr Surg. 2017.
  4. Rokohl AC, Koch KR, Adler W, Trester M, Trester W, Pine NS, et al. Concerns of anophthalmic patients-a comparison between cryolite glass and polymethyl methacrylate prosthetic eye wearers. Graefes Arch Clin Exp Ophthalmol. 2018.
  5. Rokohl AC, Mor JM, Trester M, Koch KR, Heindl LM. [Rehabilitation of Anophthalmic Patients with Prosthetic Eyes in Germany Today - Supply Possibilities, Daily Use, Complications and Psychological Aspects]. Klin Monbl Augenheilkd. 2019;236(1):54-62.
  6. Rokohl AC, Koch KR, Trester M, Heindl LM. [Cryolite glass ocular prostheses and coralline hydroxyapatite implants for eye replacement following enucleation]. Ophthalmologe. 2018;115(9):793-4.
  7. Thiesmann R, Anagnostopoulos A, Stemplewitz B. [Long-term results of the compatibility of a coralline hydroxyapatite implant as eye replacement]. Ophthalmologe. 2018;115(2):131-6.
  8. Cleres B, Meyer-Rusenberg HW. [Porous orbital implants]. Ophthalmologe. 2014;111(6):572-6.
  9. Norda AG, Meyer-Rusenberg HW. [Experience with orbital implants in particular with porous hydroxyapatite materials]. Ophthalmologe. 2003;100(6):437-44.
  10. Norda AG, Meyer-Rusenberg HW. [Long-term results of implantation of hydroxylapatite as artificial eye]. Ophthalmologe. 2000;97(2):91-9.
  11. Wladis EJ, Aakalu VK, Sobel RK, Yen MT, Bilyk JR, Mawn LA. Orbital Implants in Enucleation Surgery: A Report by the American Academy of Ophthalmology. Ophthalmology. 2017.
  12. Maskey B, Mathema SRB, Shrestha K, Bhochhibhoya A. A Simplified Approach to Fabricate a Hollow Ocular Prosthesis. J Prosthodont. 2018.
  13. Pine K, Sloan B, Stewart J, Jacobs RJ. Concerns of anophthalmic patients wearing artificial eyes. Clin Exp Ophthalmol. 2011;39(1):47-52.
  14. Rokohl AC, Trester M, Pine KR, Heindl LM. Risk of breakage of cryolite glass prosthetic eyes. Graefes Arch Clin Exp Ophthalmol. 2019;257(2):437-8.
  15. Cote RE, Haddad SE. Fitting a prosthesis over phthisis bulbi or discolored blind eyes. Adv Ophthalmic Plast Reconstr Surg. 1990;8:136-45.
  16. Pine NS, de Terte I, Pine KR. An investigation into discharge, visual perception, and appearance concerns of prosthetic eye wearers. Orbit. 2017;36(6):401-6.
  17. Pine NS, De Terte I, Pine KR, . Time Heals: An Investigation into How Anophthalmic Patients Feel about Eye Loss and Wearing a Prosthetic Eye. J Ophthalmol and Vis Sci. 2017;2(2): 1018.
  18. Pine NS, De Terte I, Pine KR. The Impact of Eye Loss and Prosthetic Eye Wear on Recreational, Occupational and Social Areas of Functioning. J Ophthalmol and Vis Sci. 2017;2(1): 1016.
  19. Pine KR, Sloan B, Jacobs RJ. Deposit buildup on prosthetic eyes and implications for conjunctival inflammation and mucoid discharge. Clin Ophthalmol. 2012;6:1755-62.
  20. Pine KR, Sloan B, Stewart J, Jacobs RJ. The response of the anophthalmic socket to prosthetic eye wear. Clin Exp Optom. 2013;96(4):388-93.
  21. Noble RI, Hill JC, Webb C. The dry socket--a new lubricant (safflower oil). Can J Ophthalmol. 1973;8(1):59-62.
  22. Bozkurt B, Akyurek N, Irkec M, Erdener U, Memis L. Immunohistochemical findings in prosthesis-associated giant papillary conjunctivitis. Clin Exp Ophthalmol. 2007;35(6):535-40.
  23. Pine KR, Sloan BH, Jacobs RJ. A proposed model of the response of the anophthalmic socket to prosthetic eye wear and its application to the management of mucoid discharge. Med Hypotheses. 2013;81(2):300-5.
  24. Meisler DM, Krachmer JH, Goeken JA. An immunopathologic study of giant papillary conjunctivitis associated with an ocular prosthesis. Am J Ophthalmol. 1981;92(3):368-71.
  25. Bohman E, Roed Rassmusen ML, Kopp ED. Pain and discomfort in the anophthalmic socket. Curr Opin Ophthalmol. 2014;25(5):455-60.
  26. Jones CA, Collin JR. A classification and review the causes of discharging sockets. Trans Ophthalmol Soc U K. 1983;103 ( Pt 3):351-3.
  27. Pine KR, Sloan BH, Jacobs RJ.  Clinical ocular prosthetics 1st ed. 1st ed. Berlin: Springer International 325 Publishing; 2015.
  28. Pine K, Sloan B, Stewart J, Jacobs RJ. A survey of prosthetic eye wearers to investigate mucoid discharge. Clin Ophthalmol. 2012;6:707-13.
  29. Bailey CS, Buckley RJ. Ocular prostheses and contact lenses. I--Cosmetic devices. BMJ. 1991;302(6783):1010-2.
  30. Quaranta-Leoni FM. Treatment of the anophthalmic socket. Curr Opin Ophthalmol. 2008;19(5):422-7.
  31. Ibrahiem MF, Abdelaziz ST. Shallow Inferior Conjunctival Fornix in Contracted Socket and Anophthalmic Socket Syndrome: A Novel Technique to Deepen the Fornix Using Fascia Lata Strips. J Ophthalmol. 2016;2016:3857579.
  32. Keseru M, Grosse Darrelmann B, Green S, Galambos P. [Post enucleation socket syndrome - new and established surgical solutions]. Klin Monbl Augenheilkd. 2015;232(1):40-3.
  33. Hatt M. [Orbitoplasty in patients with artificial eyes]. Klin Monbl Augenheilkd. 1992;200(5):424-7.
  34. Kwitko GM, Patel BC. Blepharoplasty, Ptosis Surgery.  StatPearls. Treasure Island (FL)2018.
  35. Kim SS, Kawamoto HK, Kohan E, Bradley JP. Reconstruction of the irradiated orbit with autogenous fat grafting for improved ocular implant. Plast Reconstr Surg. 2010;126(1):213-20.
  36. Chin K, Margolin CB, Finger PT. Early ocular prosthesis insertion improves quality of life after enucleation. Optometry. 2006;77(2):71-5.
  37. Hintschich C, Baldeschi L. [Rehabilitation of anophthalmic patients. Results of a survey]. Ophthalmologe. 2001;98(1):74-80.
  38. Neimkin MG, Custer PL. Compliance With Protective Lens Wear in Anophthalmic Patients. Ophthal Plast Reconstr Surg. 2017;33(1):61-4.


MRGC, eine retinale „Schlüssel“-Zelle

Peter Heilig

Seiten 23–24

  1. Quattrochi LE et al. (2019) The M6 cell: A small-field bistratified photosensitive ganglion cell. J Comp Neurol 1;527 (1): 297-311
  2. Lledo VE et al. (2019) Yellow Filter Effect on Melatonin Secretion in the Eye: Role in IOP Regulation. J Current Eye Research 44 (6):614-618