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Schwerpunkt: Cornea

 

Aniridie bei PAX6-Syndrom: Eine potenziell zur Erblindung führende Erkrankung – Etablierung eines Deutschen Aniridie-Registers

Barbara Käsmann-Kellner, Berthold Seitz

Seiten 12

  1. Käsmann-Kellner B, Seitz B.  Aniridiesyndrom: Klinische Befunde, problematische Verläufe und Vorschlag zur Betreuungsoptimierung („Aniridielotse“). Ophthalmologe 2014; 111:1145–1156
  2. Käsmann-Kellner B. and Seitz B.  Kongenitale Aniridie oder PAX6-Syndrom? Ophthalmologe 2014; 111: 1144–1144
  3. Hingorani M, Hanson I, van Heyningen V. Aniridia. Eur J Hum Genet 2012; 20:1011–1017
  4. Miller RW, Fraumeni JFJ, Manning MD. Association of Wilms tumor with aniridia, hemihypertrophy and other congenital malformations. N Engl J Med 1964; 270:922–927
  5. Rohbach JM. Zur Geschichte der Aniridie. Klin Monbl Augenheilkd 2018; 35:324-329
  6. Seitz B, Käsmann-Kellner B, Viestenz A. Stadiengerechte Therapie der kongenitalen Aniridie. Ophthalmologe 2014; 111:1164–1171
  7. Viestenz AR, Seitz B, Deland E, Fiorentzis M. Latta L, Viestenz AN, Käsmann-Kellner B. Clinical anatomy of the anterior chamber angle in congenital aniridia – and consequences for trabeculotomy/cyclophotocoagulation. Clin Anat 2018; 31:64-67
  8. Ihnatko R, Eden U, Fagerholm P, Lagali N. Congenital aniridia and the ocular surface. Ocul Surf 2016; 14:196–206
  9. Cursiefen C, Kruse FE, Naumann GOH. Cornea und Limbus. In: Angewandte Anatomie für ophthalmische Mikrochirurgen. Ed: Naumann GOH, Holbach L, Kruse FE. Springer Berlin Heidelberg, 2008, Druck ISBN 978-3-540-24189-8
  10. Latta L, Viestenz Ar, Stachon T, Colanesi S, Szentmáry N, Seitz B, Käsmann-Kellner B. Human aniridia limbal epithelial cells lack expression of keratins K3 and K12. Exp Eye Res 2018; 167:100-109
  11. Käsmann-Kellner B, Latta L, Fries F, Viestenz AR, Seitz B: Diagnostic impact of anterior segment angiography of limbal stem cell insufficiency in PAX6 related aniridia. Clin Anat 2018; 31:392-397

 

Verätzungstherapie

Norbert Schrage

Seiten 19-25

  1. Hall AH, Maibach HI (2006) Water decontaminati- on of chemical skin/eye splashes: a critical review.  Cutan Ocul Toxicol 25(2):67–83
  2. Best F (1951) Therapy of fresh lime burns of the  eye with hydrochloric acid. Ophthalmologica  122(1):58–63
  3. Hall AH, Blomet J, Mathieu L (2002) Diphoterine  for emergent eye/skin chemical splash decontamination: a review. Vet Hum Toxicol 44(4):228–231
  4. Graupner OK, Kaelman EV, LePetit GF (1971) Die  Bedeutung der Puffereigenschaften von Hornhaut  und Kammerwasser für den Schutz des Auges bei  Verätzungen. Albrecht v Graefes Clin Exp Ophthal- mol 182:351–356
  5. Laux U, Roth HW, Krey H, Steinhardt B (1975) Die  Wasserstoffkonzentration des Kammerwassers  nach Alkaliverätzungen der Hornhaut und deren  therapeutische Beeinflußbarkeit. Eine tierexperi- mentelle Studie. Albrecht v Graefes Arch Clin Exp  Ophthalmol 195(1):33–40
  6. Kompa S, Redbrake C, Hilgers C, Wüstemeyer H, Schrage N, Remky A. (2005) Effect of different irrigating solutions on aqueous humour pH changes, intraocular pressure and histological findings after induced alkali burns. Acta Ophthalmol Scand 83(4):467-470
  7. Rihawi S, Frentz M, Becker J, Reim M, Schrage NF. (2007) The consequences of delayed intervention when treating chemical eye burns.  Graefes Arch Clin Exp Ophthalmol 245(10):1507-1513.
  8. Merle H, Donnio A, Ayeboua L, Michel F, Thomas F, Ketterle J, Leonard C, Josset P, Gerard M. (2005) Alkali ocular burns in Martinique (French West Indies):  Evaluation of the use of an amphoteric solution as the rinsing product. Burns 31(2):205-211.
  9. N.Wiesner, R. M. Dutescu, D. Uthoff, A. Kottek, M. Reim, N. Schrage: First Aid Therapy for Corrosive Chemical Eye Burns:  Results of a 30-year Longitudinal Study with Two Different Decontamination Concepts. Graefes Archives Exp Clin eye res. 2019 (in press)
  10. Schrage NF, Schlossmacher B, Aschenbrenner W, Langefeld S. (2001) Phosphate buffer in alkali eye burns as an inducer of experimental corneal calcification. Burns 27(5):459-464.
  11. Schrage NF1,2, Abu Sabah S2, Hermanns L1, Panfil C1. Dutescu RM1,2.: Irrigation with phosphate-buffered saline causes corneal calcification during treatment of ocular burns; Burns (2019) in press
  12. Schrage NF, Frentz M, Reim M. (2010) Changing the composition of buffered eye-drops prevents undesired side effects.  Br J Ophthalmol 94(11):1519-1522.
  13. Steinemann A et al. Corneal Endothelial Decompensation after Ocular Chemical Burn: Description of a New Finding. Klin Monatsbl Augenheilkd 2019; 236: 371–376).

 

100 Jahre Fuchs-Endotheldystrophie: Erstbeschreibung bis zur Endothelzell-Injektion

Mario Matthaei, Sebastian Siebelmann, Björn Bachmann, Claus Cursiefen

Seiten 26-29

  1. Gain P, Jullienne R, He Z, Aldossary M, Acquart S, Cognasse F, Thuret G (2016) Global Survey of Corneal Transplantation and Eye Banking. JAMA ophthalmology 134 (2):167-173. doi:10.1001/jamaophthalmol.2015.4776
  2. Muller A, McGhee CN (2003) Professor Ernst Fuchs (1851-1930): a defining career in ophthalmology. Arch Ophthalmol 121 (6):888-891. doi:10.1001/archopht.121.6.888
  3. Fuchs E (1910) Dystrophia epithelialis corneae. Albr von Græfe’s Arch für Ophthalmol 76 (3):478–508
  4. Koeppe L (1916) Klinische Beobachtungen mit der Nernstspaltlampe und dem Hornhautmikroskop. Albr von Græfe’s Arch für Ophthalmol 91 (3):363-379
  5. Kraupa E (1920) Pigmentierungen der Hornhauthinterfläche bei Dystrophia epithelialis (Fuchs). Zeitschrift für Augenheilkunde Basel 44:247-250
  6. Vogt A (1921) Weitere Ergebnisse der Spaltlampenmikroskopie des vordern Bulbusabschnittes. . Arch Ophthalmol (63–113)
  7. Friedenwald H, Friedenwald J (1925) Epithelial dystrophy of the cornea. Br J Ophthalmol 9 (1):14-20
  8. Yee RW, Matsuda M, Schultz RO, Edelhauser HF (1985) Changes in the Normal Corneal Endothelial Cellular-Pattern as a Function of Age. Current Eye Research 4 (6):671-678. doi:Doi 10.3109/02713688509017661
  9. Vedana G, Villarreal G, Jr., Jun AS (2016) Fuchs endothelial corneal dystrophy: current perspectives. Clinical ophthalmology 10:321-330. doi:10.2147/OPTH.S83467
  10. Wilson SE, Bourne WM (1988) Fuchs' dystrophy. Cornea 7 (1):2-18
  11. Waring GO, 3rd (1982) Posterior collagenous layer of the cornea. Ultrastructural classification of abnormal collagenous tissue posterior to Descemet's membrane in 30 cases. Arch Ophthalmol 100 (1):122-134
  12. Matthaei M, Leitl C, Cursiefen C, Heindl LM (2018) Correlation of extracellular matrix-related gene expression with objective Fuchs endothelial corneal dystrophy severity. Clinical & experimental ophthalmology. doi:10.1111/ceo.13461
  13. Adamis AP, Filatov V, Tripathi BJ, Tripathi RC (1993) Fuchs' endothelial dystrophy of the cornea. Surv Ophthalmol 38 (2):149-168
  14. Mootha VV, Hansen B, Rong Z, Mammen PP, Zhou Z, Xing C, Gong X (2017) Fuchs' Endothelial Corneal Dystrophy and RNA Foci in Patients With Myotonic Dystrophy. Invest Ophthalmol Vis Sci 58 (11):4579-4585. doi:10.1167/iovs.17-22350
  15. Olsen T (1984) Is there an association between Fuchs' endothelial dystrophy and cardiovascular disease? Graefes Arch Clin Exp Ophthalmol 221 (5):239-240
  16. Lipman RM, Rubenstein JB, Torczynski E (1990) Keratoconus and Fuchs' corneal endothelial dystrophy in a patient and her family. Archives of ophthalmology 108 (7):993-994
  17. Pitts JF, Jay JL (1990) The association of Fuchs's corneal endothelial dystrophy with axial hypermetropia, shallow anterior chamber, and angle closure glaucoma. Br J Ophthalmol 74 (10):601-604
  18. Nagarsheth M, Singh A, Schmotzer B, Babineau DC, Sugar J, Lee WB, Iyengar SK, Lass JH, Fuchs' Genetics Multi-Center Study G (2012) Relationship Between Fuchs Endothelial Corneal Dystrophy Severity and Glaucoma and/or Ocular Hypertension. Archives of ophthalmology 130 (11):1384-1388. doi:10.1001/archophthalmol.2012.1969
  19. Matthaei M, Elsner E, Caramoy A, Adler W, Siebelmann S, Schaub F, Skevas C, Liakopoulos S, Bachmann B, Cursiefen C, Heindl LM (2018) Fuchs endothelial corneal dystrophy and macular drusen: evidence for coincidence? Eye (Lond) 32 (4):840-841. doi:10.1038/eye.2017.301
  20. Rao GP, Kaye SB, Agius-Fernandez A (1998) Central corneal endothelial guttae and age-related macular degeneration: is there an association? Indian journal of ophthalmology 46 (3):145-147
  21. Lorenzetti DW, Uotila MH, Parikh N, Kaufman HE (1967) Central cornea guttata. Incidence in the general population. Am J Ophthalmol 64 (6):1155-1158
  22. Krachmer JH, Purcell JJ, Jr., Young CW, Bucher KD (1978) Corneal endothelial dystrophy. A study of 64 families. Arch Ophthalmol 96 (11):2036-2039
  23. Schaub F, Enders P, Bluhm C, Bachmann BO, Cursiefen C, Heindl LM (2017) Two-year course of corneal densitometry after Descemet membrane endothelial keratoplasty. Am J Ophthalmol 175:60-67. doi:10.1016/j.ajo.2016.11.019
  24. Wacker K, Baratz KH, Bourne WM, Patel SV (2018) Patient-Reported Visual Disability in Fuchs' Endothelial Corneal Dystrophy Measured by the Visual Function and Corneal Health Status Instrument. Ophthalmology 125 (12):1854-1861. doi:10.1016/j.ophtha.2018.06.018
  25. Seitz B, Hager T (2016) Clinical Phenotypes of Fuchs Endothelial Corneal Dystrophy (FECD), Disease Progression, Differential Diagnosis, and Medical Therapy. In: Cursiefen C, Jun AS (eds) Current Treatment Options for Fuchs Endothelial Dystrophy. Springer, pp 25-50
  26. Wieben ED, Aleff RA, Tosakulwong N, Butz ML, Highsmith WE, Edwards AO, Baratz KH (2012) A common trinucleotide repeat expansion within the transcription factor 4 (TCF4, E2-2) gene predicts Fuchs corneal dystrophy. Plos One 7 (11):e49083. doi:10.1371/journal.pone.0049083
  27. Baratz KH, Tosakulwong N, Ryu E, Brown WL, Branham K, Chen W, Tran KD, Schmid-Kubista KE, Heckenlively JR, Swaroop A, Abecasis G, Bailey KR, Edwards AO (2010) E2-2 protein and Fuchs's corneal dystrophy. N Engl J Med 363 (11):1016-1024. doi:10.1056/NEJMoa1007064
  28. Soliman AZ, Xing C, Radwan SH, Gong X, Mootha VV (2015) Correlation of Severity of Fuchs Endothelial Corneal Dystrophy With Triplet Repeat Expansion in TCF4. JAMA ophthalmology 133 (12):1386-1391. doi:10.1001/jamaophthalmol.2015.3430
  29. Matthaei M, Sandhaeger H, Hermel M, Adler W, Jun AS, Cursiefen C, Heindl LM (2017) Changing Indications in Penetrating Keratoplasty: A Systematic Review of 34 Years of Global Reporting. Transplantation 101 (6):1387-1399. doi:10.1097/TP.0000000000001281
  30. Melles GR, Ong TS, Ververs B, van der Wees J (2006) Descemet membrane endothelial keratoplasty (DMEK). Cornea 25 (8):987-990. doi:10.1097/01.ico.0000248385.16896.34
  31. Melles GR (2006) Posterior lamellar keratoplasty: DLEK to DSEK to DMEK. Cornea 25 (8):879-881. doi:10.1097/01.ico.0000243962.60392.4f00003226-200609000-00003 [pii]
  32. Matthaei M, Schrittenlocher S, Hos D, Siebelmann S, Bucher F, Schaub F, Hoerster R, Siggel R, Roters S, Heindl LM, Bachmann B, Cursiefen C (2018) [10 years of Descemet membrane endothelial keratoplasty in Fuchs endothelial corneal dystrophy : What have we learned?]. Ophthalmologe. doi:10.1007/s00347-018-0800-3
  33. Soh YQ, Peh GS, Mehta JS (2018) Evolving therapies for Fuchs' endothelial dystrophy. Regen Med 13 (1):97-115. doi:10.2217/rme-2017-0081
  34. Kinoshita S, Koizumi N, Ueno M, Okumura N, Imai K, Tanaka H, Yamamoto Y, Nakamura T, Inatomi T, Bush J, Toda M, Hagiya M, Yokota I, Teramukai S, Sotozono C, Hamuro J (2018) Injection of cultured cells with a ROCK inhibitor for bullous keratopathy. N Engl J Med 378 (11):995-1003. doi:10.1056/NEJMoa1712770
  35. Matthaei M, Hu J, Kallay L, Eberhart CG, Cursiefen C, Qian J, Lackner EM, Jun AS (2014) Endothelial cell microRNA expression in human late-onset Fuchs' dystrophy. Invest Ophthalmol Vis Sci 55 (1):216-225. doi:10.1167/iovs.13-12689
  36. Soh YQ, Mehta JS (2018) Regenerative Therapy for Fuchs Endothelial Corneal Dystrophy. Cornea 37 (4):523-527. doi:10.1097/ICO.0000000000001518

 

Was tun bei negativen Dysphotopsien?

Interview mit Tobias Neuhann

Seiten 30-32

  1. Davison JA (2000) Positive and negative dysphotosia in patients with acrylic intraocular lenses. J Cataract Refract Surg 26: 1346 – 355 
  2. Wenzel M, Langenbucher A: (2015) Ist die negative Dysphotopsie nach der Kataraktoperation durch den N. Opticus und den blinden Fleck beeinflusst? Deutschsprachige Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie. 29. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII). Karsruhe, 26.-28.02.2015. Düsseldorf: German Medical Science GMS Publishing House;. Doc15dgii074 (15dgii074)
  3. Wenzel M, Langenbucher A, Eppig T (2017) Ursachen, Diagnose und Therapie der negativen Dysphotopsie. Klin Monbl Augenheilkd; doi: 10.1055/s-0043-112855 
  4. Masket, Samuel et al. (2018) Surgical management of negative dysphotopsia. J Cataract Refract Surg 44 ,1 , 6 – 16
  5. Holladay JT, Simpson MJ, (2017) Negative dysphotopsia Causes and rational for prevention and treatment. J Cataract Refract Surg 43: 263 – 275 
  6. Makhotkina NY, Berendschot TT, Nuijts RM. (2016) Objective evaluation of negative dysphotopsia with Goldmann kinetic perimetry. J Cataract Refract Surg. 2016 Nov;42(11):1626-1633. doi: 10.1016/j.jcrs.2016.09.016.
  7. Coroneo MT, Pham T, Kwok LS. (2003) Off-axis edge glare in pseudophakic dysphotopsia. J Cataract Refract Surg. 2003 Oct;29(10):1969-73.
  8. Hu J, Sella R, Afshari NA (2018) Dysphotopsia: a multifaceted optic phenomenon Curr Opin Ophthalmol.  Jan;29(1):61-68. 
  9. Masket S, Fram NR. (2011)Pseudophakic negative dysphotopsia: Surgical management and new theory of etiology. J Cataract Refract Surg. 2011 Jul;37(7):1199-207. 
  10. Neuhann T (1991) The Rhexis-fixated Lens. ASCRS FilmFestival Boston . Runner-up Award
  11. Neuhann T (1991) When posterior capsule tears, use capsulorhexis for IOL fixation, PHACO&FOLDABLES; 4(6):1,3.
  12. Masket S, Fram NR, Cho A, Park I, Pham D. (2018) Surgical management of negative dysphotopsia. J Cataract Refract Surg.;44(1):6-16)
  13. Alapati N.M., Harocopos G.J., Sheybani A. (2016) In-the-bag nasal intraocular lens optic truncation for treatment of negative dysphotopsia. Journal of Cataract and Refractive Surgery,  42  (12) , pp. 1702-1706.
  14. Scharioth G (2018) Negative Dysphotopsie: In jedem Fall ernst nehmen! Ophthalmo-Chirurgie 30: XX – XX 
  15. Vámosi P, Csákány B, Németh J. (2010) Intraocular lens exchange in patients with negative dysphotopsia symptoms. J Cataract Refract Surg. 2010 Mar;36(3):418-24.

 

Experiment Tränenfilm

Interview mit Felix Zimmermann

  1. D.H. Szczesna-Iskander, D. Alonso-Caneiro, D.R. Iskander, Objective Measures of Pre-lens Tear Film Dynamics versus Visual Responses, Optom. Vis. Sci. 93 (2016) 872–880. doi.org/10.1097/OPX.0000000000000876.
  2. M. Kaido, Functional Visual Acuity, Invest. Ophthalmol. Vis. Sci. 59 (2018) DES29-DES35. doi.org/10.1167/iovs.17-23721.
  3. J. Rumpakis, New Data on Contact Lens Dropouts: An International Perspective, Review of Optometry 1 (2010).
  4. J.K. Portello, M. Rosenfield, C.A. Chu, Blink rate, incomplete blinks and computer vision syndrome, Optom. Vis. Sci. 90 (2013) 482–487. doi.org/10.1097/OPX.0b013e31828f09a7.
  5. A.J. Koivisto, T. Hussein, R. Niemelä, T. Tuomi, K. Hämeri, Impact of particle emissions of new laser printers on modeled office room, Atmospheric Environment 44 (2010) 2140–2146. doi.org/10.1016/j.atmosenv.2010.02.023.