Das Medizinportal


Endothelzelldichte: Welche Konsequenzen ergeben sich für die moderne Katarakt-Operation? (S. 14-17)
C. Latz
1.    Vogt A. Lehrbuch und Atlas der Spaltlampenmikroskopie des Lebenden Auges. Julius Springer. Berlin 1930; 1
2.    Mishima S. Clinical Investigations on the Corneal Endothelium. Am. J.Ophthalmol. 1982;93:(1) 1-29
3.    Philips C, Laing R, Yee R. Specular Microscopy. In J.H. Krachmer, M.J. Mannis, and E.J. Holland (Eds.) Cornea, Volume one: Fundamentals, Diagnosis and Management, second edition. Elsevier Mosby publishing Inc. (2005).
4.    Taing RA, Sandstrom MM, Berrospi AR, and Leibowitz HM. Changes in the corneal endothelium as a function of age. Exp. Eye Res. 1976;22(6):587-594
5.    Olsen LE, Marshall J, Rice NS, Andrews R: Effects of ultrasound on the corneal endothelium: II. The endothelial repair process, Br J Ophthalmol. 1978 Mar; 62(3): 145–154.
6.    Borkar DS, Veldman P, Colby KA. Treatment of Fuchs endothelial dystrophy by Descemet stripping without endothelial keratoplasty. Cornea 2016; 35:1267–1273
7.    Kaufman AR, Nosé RM, Lu Y, Pineda RII. Phacoemulsification with intraocular lens implantation after previous descemetorhexis without endothelial keratoplasty. J Cataract Refract Surg. 2017 Nov;43(11):1471-1475.
8.    Srinivas SP, Ong A, Zhai CB, Bonanno JA. Inhibition of Carbonic Anhydrase Activity in Cultured Bovine Corneal Endothelial Cells by Dorzolamide.Invest. Ophthalmol. Vis. Sci. 2002;43(10):3273-3278
9.    Niederer RL, Perumal D, Sherwin T, McGhee CN. Age-related differences in the normal human cornea: a laser scanning in vivo confocal microscopystudy. Br J Ophthalmol. 2007 Sep;91(9):1165-9.
10.    Lechner S, Schweig F, Rieck P, Anders N, Hartmann C. Pathologisch verminderte Endothelzellzahl spaltlampenmikroskopsch unauffälliger Hornhaut: Ein wichtiger Befund vor der Kataraktchirurgie. Ophthalmologe. 2001 Mar; 98(3): 273-276
11.    Sorrentino FS, Matteini S, Imburgia A, Bonifazzi C, Sebastiani A, Parmeggiani F. Torsional phacoemulsification: A pilot study to revise the “harm scale” evaluating the endothelial damage and the visual acuity after cataract surgery. PLoS ONE 2017;12(10): e0186975
12.    O'Brien, Paul D et al. Risk factors for endothelial cell loss after phacoemulsification surgery by a junior resident. J Cataract Refract Surg.2004;30(4):839 – 843
13.    Arshinoff SA, Norman R.Tri-soft shell technique. J Cataract Refract Surg. 2013;39 (8):1196 – 1203
14.    Baydoun L, van Dijk K, et al..Repeat Descemet Membrane Endothelial Keratoplasty after Complicated Primary Descemet Membrane Endothelial Keratoplasty. Ophthalmology.2015; 122 (1): 8 – 16
15.    Milojcic C, Latz C, Tandogan T et al. Ophthalmologe.2017; 114 (9): 832-837
16.    Ham L, Dapena I, et al. Refractive change and stability after Descemet membrane endothelial keratoplasty. J Cataract Refract Surg. 2011; 37 (8 ):1455 - 1464

IOL-Eintrübungen: Ursachen und Therapiemöglichkeiten (S. 18-21)

A.C. Klein, M. Kohlhaas
1.         Apple DJ, Sims J. Harold Ridley and the invention of the intraocular lens. Surv Ophthalmol. 1996; 40(4):279-92.
2.         Auffarth GU, Apple DJ. Zur Entwicklungsgeschichte der Intraokularlinsen. Der Ophthalmologe. 2001; 98. 1017-1028.
3.         Rezaei-Kanavi M, Javadi M-A, Mirbabaei-Ghafghazi F. Intraocular Lens Calcification: a Clinicopathologic Report. J Ophthalmic Vis Res. 2009 Apr; 4(2):122-124.
4.         Neuhann IM, Kleinmann G, Apple DJ. A New Classification of Calcification of Intraocular Lenses. Ophthalmology. 2008; 115. 73-9.
5.         Milojcic C, Latz, C, Tandogan, T, Auffarth GU, Holz FG, Choi CY, Khoramnia R. (2016). Eintrübung einer hydrophilen Acryl-Intraokularlinse nach DMEK: Eine Materialanalyse. Der Ophthalmologe. 2017; 114: 832-837.
6.         Fung SSM, Sykakis E, Islam NM, Zambarakji HJ, Khoramnia R, Auffarth GU, Parma DN. Intraocular Lens Opacification following Intracameral Injection of Recombinant Tissue Plasminogen Activator to Treat Inflammatory Membranes after Cataract Surgery. Journal of Ophthalmology 2015; 2015:975075, 6 pages.
7.         Giers, BC; Tandogan T, Auffarth GU, Choi CY, Auerbach FN, Sel S, Mayer C, Khoramnia R. Hydrophilic intraocular lens opacification after posterior lamellar keratoplasty – a material analysis with special reference to optical quality assessment. BMC Ophthalmol. 2017 Aug 22; 17(1):150. doi: 10.1186/s12886-017-0546-8.
8.         Morgan-Warren PJ, Andreatta W, Patel AK. Opacification of hydrophilic intraocular lenses after Descemet stripping automated endothelial keratoplasty. Clin Ophthalmol (Auckland, NZ). 2015; 9:277-283.
9.         Werner L, Glistenings and surface light scattering in intraocular lenses. J Cataract Refract Surg. 2010: Volume 36, Issue 8, 1398-1420.
10.       Schmidbauer JM , Werner L, Apple DJ , Pandey SK , Izak AM, Trivedi RH, Macky TA, Auffarth GU , Peng Q, Arthur SN, Escobar-Gomez M,  Ma L, Vargas LG. Postoperative Trübungen von Hinterkammerlinsen – eine Übersicht. Klin Monbl Augenheilkd. 2001; 218(9): 586-594.
11.       Wang Q, Merz PR, Fang H, Schickhardt SK, Rabsilber TM, Auffarth GU. Evaluation von Glistenings in der ersten Generation der AcrySof Intraokularlinsen aus den 1990er Jahren. Deutschsprachige Gesellschaft für Intraokularlinsen-Implantation, Interventionelle und Refraktive Chirurgie (DGII). Meeting Abstract. 2017.
12.       Matsushima H, Mukai K, Nagata M, Gotoh N, Matsui E, Senoo T. Analysis of surface whitening of extracted hydrophobic acrylic intraocular lenses. J Cataract Refract Surg. 2009; Volume 35 , Issue 11, 1927-1934.
13.       Apple DJ, Peng Q, Arthur SN, Werner L, Merritt JH, Vargas LG, Hoddinott DS, Escobar-Gomez M, Schmidbauer JM. Snowflake degeneration of polymethyl methacrylate posterior chamber intraocular lens optic material: a newly described clinical condition caused by unexpected late opacification of polymethyl methacrylate. Ophthalmology. 2002; 109(9): 1666-75.
14.       Werner L, Stover JC, Schwiegerling J, Das KK. Effects of Intraocular Lens Opacification on Light Scatter, Stray Light, and Overall Optical Quality/Performance. Invest. Ophthalmol. Vis. Sci. 2016; 57(7):3239-3247.
15.       Schmidbauer JM, Apple DJ, Peng Q, Arthur SN,Vargas LG. Trübung einer PMMA-Intraokularlinse. Der Ophthalmologe. 2002; Volume 99, Issue 4, 306–307.
16.       Fernández-Buenaga R, Alió JL. Intraocular Lens Explantation After Cataract Surgery: Indications, Results, and Explantation Techniques. Asia Pac J Ophthalmol (Phila). 2017; 6(4):372-380.
17.       Schulze S, Bertelmann T, Sekundo W. Implantation von Intraokularlinsen in den Sulcus ciliaris. Der Ophthalmologe. 2014; Volume 111, Issue 4, 305–309.

Planung, Markierung und Tracking bei torischer Linsenimplantation: Manuell versus digital (S. 22-23)
W.J. Mayer
1. Visser N, Berendshot TT, Bauer NJ, Jurich J, Kersting O, Nuijts RM (2011) Accuracy of toric intraocular lens implantation in cataract and refractive surgery. J Cataract Refract Surg 37: 1394 – 402
2. Viestenz A, Seitz B, Langenbucher A (2005) Evaluating the eye´s rotational stability during standard photography: effect on determining the axial orientation of toric intraocular lenses. J Cataract Refract Surg 31: 557 – 61
3. Mayer WJ, Kreutzer T, Dirisamer M, Kern C, Kortuem K, Vounotrypidis E, Priglinger S, Kook D (2017) Comparison of visual outcomes, alignment accuracy, and surgical time between 2 methods of corneal marking for toric intraocular lens implantation. J Cataract Refract Surg 43: 1281 – 1286

Patienten profitieren von maßgeschneiderten Intraokularlinsen (S. 24-32)
J. Schrecker
1.    Oshika T, Tokunaga T, Samejima T, Miyata K, Kawana K, Kaji Y. Influence of Pupil Diameter on the Relation between Ocular Higher-Order Aberration and Contrast Sensitivity after Laser In Situ Keratomileusis. Investigative Ophthalmology & Visual Science. 2006;47(4):1334-8.
2.    Hayashi K, Yoshida M, Hayashi H. Correlation of higher-order wavefront aberrations with visual function in pseudophakic eyes. Eye (Lond). 2008;22(12):1476-82.
3.    Piers PA, Manzanera S, Prieto PM, Gorceix N, Artal P. Use of adaptive optics to determine the optimal ocular spherical aberration. J Cataract Refract Surg. 2007;33(10):1721-6.
4.    Piers PA, Fernandez EJ, Manzanera S, Norrby S, Artal P. Adaptive optics simulation of intraocular lenses with modified spherical aberration. Invest Ophthalmol Vis Sci. 2004;45(12):4601-10.
5.    Smith G, Cox MJ, Calver R, Garner LF. The spherical aberration of the crystalline lens of the human eye. Vision Research. 2001;41(2):235-43.
6.    Glasser A, Campbell MC. Presbyopia and the optical changes in the human crystalline lens with age. Vision Res. 1998;38(2):209-29.
7.    Yamaguchi T, Dogru M, Yamaguchi K, Ono T, Saiki M, Okuyama H, et al. Effect of spherical aberration on visual function under photopic and mesopic conditions after cataract surgery. J Cataract Refract Surg. 2009;35(1):57-63.
8.    Holladay JT, Piers PA, Koranyi G, van der Mooren M, Norrby NE. A new intraocular lens design to reduce spherical aberration of pseudophakic eyes. J Refract Surg. 2002;18(6):683-91.
9.    Beiko GH, Haigis W, Steinmueller A. Distribution of corneal spherical aberration in a comprehensive ophthalmology practice and whether keratometry can predict aberration values. J Cataract Refract Surg. 2007;33(5):848-58.
10.    de Sanctis U, Vinai L, Bartoli E, Donna P, Grignolo F. Total spherical aberration of the cornea in patients with cataract. Optom Vis Sci. 2014;91(10):1251-8.
11.    Fang Y, Lu Y, Wu X, Miao A, Luo Y. Visual function and subjective quality of life in Chinese cataract patients after implantation with aspheric intraocular lenses. Eur J Ophthalmol. 2011;21(6):732-40.

Klinische Erfahrungen mit der Oberflächenbehandlung TransPRK (S. 27-29)
D. de Ortueta
1. Reinstein D, Archer T, Gobbe M et al. Epithelial thickness in the normal cornea: Three-dimensional Display with very high frequency ultrasound. Journal of Refractive Surgery. 2008; 24(6): 571-581
2. M.V. Netto, R.R. Mohan, S. Sinha, et al. Stromal haze, myofibroblasts, and surface irregularity after PRK. Experimental Eye Research. 2006; 82 (5): 788–797.
3. Le H, Roberts CJ, Kim TI, Ambrósio R Jr., Elsheikh A,Yong Kang DS. Changes in biomechanically corrected intraocular pressure and dynamic corneal response parameters before and after transepithelial photorefractive keratectomy and femtosecond laser-assisted laser in situ keratomileusis. Journal of Cataract & Refractive Surgery. 2017; 43(12):1495-1503.

Schichtforamen der Makula, eine Herausforderung für Klassifikation und Therapie (S. 30-34)
C. Haritoglou 
1.    Androudi S, Stangos A, Brazikitos PD. Lamellar macular holes: Tomographic features and surgical outcome. Am J Ophthalmol 2009; 148: 420-426
2.    Bottoni F, Deiro AP, Giani A, Orini C, Cigada M, Staurenghi C. The natural history of lamellar macular holes: a spectral domain optical coherence tomography study. Graefes Arch Clin Exp Ophthalmol 2013; 251: 467-475
3.    Compera D, Entchev E, Haritoglou C, Scheler R, Mayer WJ, Wolf A, Kampik A, Schumann RG. Lamellar Hole-Associated Epiretinal Proliferation in Comparison to Epiretinal Membranes of Macular Pseudoholes. Am J Ophthalmol 2015; 160(2): 373-384
4.    Gass JD. Lamellar macular hole: a complication of cystoid macular edema after cataract extraction. Arch Ophthalmol 1976; 94: 793-800
5.    Gaudric A, Aloulou Y, Tadayoni R, Massin P. Macular pseudoholes with lamellar cleavage of their edge remain pseudoholes. Am J Ophthalmol 2013; 155: 733-742
6.    Govetto A, Dacquay Y, Farajzadeh M, Platner E, Hirabayashi K, Hosseini H, Schwartz SD, Hubschmann J. Lamellar macular hole: Two distinct clinical entities? Am J Ophthalmol 2016; 164: 99-109
7.    Haouchine B, Massin P, Tadayoni R, Rginay A, Gaudric A. Diagnosis of macular Pseudoholes and lamellar macular holes by optical coherence tomography. Am J Ophthalmol 2004; 138: 732-739
8.    Hirota K, Itoh Y, Rii T, Inoue M, Hirakata A. Correlation between foveal interdigitation zone band defect and visual acuity after surgery for macular pseudohole. Retina 2015; 35(5): 908-14
9.    Lai T, Chen S, Yang C. Epiretinal proliferation in lamellar macular holes and full thicknes macular holes: clinical and surgical outcomes. Graefes Arch Clin Exp Ophthalmol 2016; 254: 629-638
10.    Parolini B, Schumann RG, Cereda MG, Haritoglou C, Pertile G. Lamellar macular hole: A clinicopathologic correlation of surgically excised epiretinal membranes. Invest Ophthalmol Vis Sci 2011; 52: 9074-9083
11.    Schumann RG, Compera D, Schaumberger M, Wolf A, Fazekas C, Mayer WM, Kampik A, Haritoglou C. Epiretinal membrane characteristics correlate with photoreceptor layer defects in lamellar macular holes and macular pseudoholes. Retina 2014; 0: 1-9

Das AMD-Netz informiert: Was Tablets & Co. für AMD-Patienten leisten können (S. 36)

1    Crossland MD, Silva RS, Macedo AF. Smartphone, tablet computer and e-reader use by people with vision impairment. Ophthalmic Physiol Opt. 2014 Sep;34(5):552-7. doi: 10.1111/opo.12136. Epub 2014 Jul 28.
2    Irvine D, Zemke A, Pusateri G, Gerlach L, Chun R, Jay WM.Tablet and Smartphone Accessibility Features in the Low Vision Rehabilitation. Neuroophthalmology. 2014 Mar 11;38(2):53-59. eCollection 2014.
3    Robinson JL, Braimah Avery V, Chun R, Pusateri G, Jay WM. Usage of Accessibility Options for the iPhone and iPad in a Visually Impaired Population. Semin Ophthalmol. 2017;32(2):163-171. doi: 10.3109/08820538.2015.1045151. Epub 2015 Jul 8.