Das Medizinportal


Neuerungen der ERC-Leitlinien 2015 für die kardio-pulmonale Reanimation unter besonderer Berücksichtigung kardiologischer Gesichtspunkte 
Frank Spillmann, Gunther Schmidt, Burkert Pieske und Carsten Tschöpe 

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  10. Blom MT, Beesems SG, Homma PC, Zijlstra JA, Hulleman M, van Hoeijen DA, Bardai A, Tijssen JG, Tan HL, Koster RW: Improved survival after out-of-hospital cardiac arrest and use of automated external defibrillators. Circulation 2014; 130:1868-1875
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  14. Hallstrom AP, Cobb LA, Johnson E, Copass MK: Dispatcher assisted CPR: implementation and potential benefit. A 12-year study. Resuscitation 2003; 57:123-129
  15. Yeung J, Okamoto D, Soar J, Perkins GD: AED training and its impact on skill acquisition, retention and performance--a systematic review of alternative training methods. Resuscitation 2011; 82:657-664
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  21. Hollenbeck RD, McPherson JA, Mooney MR, Unger BT, Patel NC, McMullan PW, Jr., Hsu CH, Seder DB, Kern KB: Early cardiac catheterization is associated with improved survival in comatose survivors of cardiac arrest without STEMI. Resuscitation 2014; 85:88-95
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Arrhythmien und plötzlicher Herztod
N. Sawan, P. Münkler, C. Eitel, H. Thiele, R. R. Tilz

  1. Priori SG et al. 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: The Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC). European heart journal. 2015 Nov 1;36(41):2793-867. doi: 10.1093
  2. Jais P, Maury P, Khairy P et al., Elimination of local abnormal ventricular activities: a new end point for substrate modification in patients with scar-related ventricular tachycardia, Circulation 2012, 125(18):2184-2196.
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  11. Hofferberth S et al. Left thoracoscopic sympathectomy for cardiac denervation in patients with life-threatening ventricular arrhythmias. The Journal of Thoracic and Cardiovascular Surgery. 2014 Jan;147(1):404-9.
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Management des Rechtsherzversagens bei akuter Lungenembolie
Priv.-Doz. Dr. med. Mareike Lankeit 

  1. Cohen AT, Agnelli G, Anderson FA, Arcelus JI, Bergqvist D, Brecht JG, Greer IA, Heit JA, Hutchinson JL, Kakkar AK, Mottier D, Oger E, Samama MM, Spannagl M. Venous thromboembolism (VTE) in Europe. The number of VTE events and associated morbidity and mortality. Thromb Haemost 2007; 98:756-764.
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  9. Ventetuolo CE, Klinger JR. Management of acute right ventricular failure in the intensive care unit. Ann Am Thorac Soc 2014; 11:811-22.
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  12. Marti C, John G, Konstantinides S, Combescure C, Sanchez O, Lankeit M, Meyer G, Perrier A. Systemic thrombolytic therapy for acute pulmonary embolism: a systematic review and meta-analysis. Eur Heart J 2015; 36:605-614.
  13. Lankeit M, Konstantinides S. Thrombolyse bei akuter Lungenembolie – Risikostratifizierung, risikoadaptierte Diagnostik und Therapie. Klinikarzt 2014; 433 (S1): 6-11.
  14. Meyer G, Vicaut E, Danays T, Agnelli G, Becattini C, Beyer-Westendorf J, Bluhmki E, Bouvaist H, Brenner B, Couturaud F, Dellas C, Empen K, Franca A, Galiè N, Geibel A, Goldhaber SZ, Jimenez D, Kozak M, Kupatt C, Kucher N, Lang IM, Lankeit M, Meneveau N, Pacouret G, Palazzini M, Petris A, Pruszczyk P, Rugolotto M, Salvi A, Schellong S, Sebbane M, Sobkowicz B, Stefanovic BS, Thiele H, Torbicki A, Verschuren F, Konstantinides SV; PEITHO Investigators. Fibrinolysis for patients with intermediate-risk pulmonary embolism. N Engl J Med 2014; 370:1402-1411.
  15. Sharifi M, Bay C, Skrocki L, Rahimi F, Mehdipour M; “MOPETT” Investigators. Moderate pulmonary embolism treated with thrombolysis (from the "MOPETT" Trial). Am J Cardiol 2013; 111:273-277.
  16. Zhang Z, Zhai ZG, Liang LR, Liu FF, Yang YH, Wang C. Lower dosage of recombinant tissue-type plasminogen activator (rt-PA) in the treatment of acute pulmonary embolism: a systematic review and meta-analysis. Thromb Res 2014; 133:357-363.
  17. Kuo WT, Gould MK, Louie JD, Rosenberg JK, Sze DY, Hofmann LV. Catheterdirected therapy for the treatment of massive pulmonary embolism: systematic review and meta-analysis of modern techniques. J Vasc Interv Radiol 2009; 20:1431–1440.
  18. Kucher N, Boekstegers P, Müller OJ, Kupatt C, Beyer-Westendorf J, Heitzer T, Tebbe U, Horstkotte J, Müller R, Blessing E, Greif M, Lange P, Hoffmann RT, Werth S, Barmeyer A, Härtel D, Grünwald H, Empen K, Baumgartner I. Randomized, controlled trial of ultrasound-assisted catheter-directed thrombolysis for acute intermediate-risk pulmonary embolism. Circulation 2014; 129:479-486.
  19. Piazza G, Hohlfelder B, Jaff MR, Ouriel K, Engelhardt TC, Sterling KM, Jones NJ, Gurley JC, Bhatheja R, Kennedy RJ, Goswami N, Natarajan K, Rundback J, Sadiq IR, Liu SK, Bhalla N, Raja ML, Weinstock BS, Cynamon J, Elmasri FF, Garcia MJ, Kumar M, Ayerdi J, Soukas P, Kuo W, Liu PY, Goldhaber SZ; SEATTLE II Investigators. A Prospective, Single-Arm, Multicenter Trial of Ultrasound-Facilitated, Catheter-Directed, Low-Dose Fibrinolysis for Acute Massive and Submassive Pulmonary Embolism: The SEATTLE II Study. JACC Cardiovasc Interv 2015; 8:1382-92. 

Chirurgische Therapie der akuten Aortendissektion Typ Stanford A
Christoph T. Starck; Jörg Kempfert; Robert Hammerschmidt, Volkmar Falk

  1. Golledge J, Eagle KA. Acute aortic dissection. The Lancet 2008;372:55–66. 
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  3. Howard DPJ, Banerjee A, Fairhead JF, Perkins J, Silver LE, Rothwell PM, on behalf of the Oxford Vascular Study. Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control: 10-Year Results From the Oxford Vascular Study. Circulation American Heart Association Journals; 2013;127:2031–2037. 
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  8. Pape LA, Awais M, Woznicki EM, Suzuki T, Trimarchi S, Evangelista A, Myrmel T, Larsen M, Harris KM, Greason K, Di Eusanio M, Bossone E, Montgomery DG, Eagle KA, Nienaber CA, Isselbacher EM, O'Gara P. Presentation, Diagnosis, and Outcomes of Acute Aortic Dissection. Journal of the American College of Cardiology 2015;66: 350–358. 
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  11. Johnson TRC, Nikolaou K, Wintersperger BJ, Knez A, Boekstegers P, Reiser MF, Becker CR. ECG-Gated 64-MDCT Angiography in the Differential Diagnosis of Acute Chest Pain. American Journal of Roentgenology 2007;188:76–82. 
  12. Hussain ST, Svensson LG. Surgical techniques in type A dissection. Annals of Cardiothoracic Surgery 2016;5:233–235. 
  13. Lu S, Yang S, Lai H, Zheng J, Hong T, Sun X, Wang C. Open aortic arch reconstruction for acute type a aortic dissection: a single-center experience with 267 consecutive patients. Journal of Cardiothoracic Surgery Journal of Cardiothoracic Surgery; 2016;:1–8. 
  14. Hata M, Orime Y, Wakui S, Nakamura T, Hinoura R, Akiyama K. Efficacy of limited proximal arch replacement for type A acute aortic dissection with critical complications. Gen Thorac Cardiovasc Surg 2016:1–2. 
  15. Kim JB, Chung CH, Moon DH, Ha GJ, Lee TY, Jung SH, Choo SJ, Lee JW. Total arch repair versus hemiarch repair in the management of acute DeBakey type I aortic dissection. European Journal of Cardio-Thoracic Surgery 2011. 
  16. Castrovinci S, Pacini D, Di Marco L, Berretta P, Cefarelli M, Murana G, Alfonsi J, Pantaleo A, Leone A, Di Eusanio M, Di Bartolomeo R. Surgical management of aortic root in type A acute aortic dissection: a propensity-score analysis. European Journal of Cardio-Thoracic Surgery 2016;50:223–229. 
  17. Leontyev S, Borger MA, Etz CD, Moz M, Seeburger J, Bakhtiary F, Misfeld M, Mohr FW. Experience with the conventional and frozen elephant trunk techniques: a single-centre study. European Journal of Cardio-Thoracic Surgery 2013;44: 1076–1083. 
  18. Tsagakis K, Pacini D, Di Bartolomeo R, Gorlitzer M, Weiss G, Grabenwoger M, Mestres CA, Benedik J, Cerny S, Jakob H. Multicenter early experience with extended aortic repair in acute aortic dissection: Is simultaneous descending stent grafting justified? The Journal of Thoracic and Cardiovascular Surgery 2010;140: S116–S120. 
  19. MBBS MS, MD TK, MD EB, MD FF, MD JU, MD FAA, MD DB, RN HK, MD AH, MD AM. Total aortic arch replacement with a novel 4-branched frozen elephant trunk prosthesis: Single-center results of the first 100 patients. The Journal of Thoracic and Cardiovascular Surgery Elsevier Inc; 2016;152: 148–159.e1. 
  20. Poon SS, Theologou T, Harrington D, Kuduvalli M, Oo A, Field M. Systematic Review Hemiarch versus total aortic arch replacement in acute type A dissection: a systematic review and meta-analysis. Annals of Cardiothoracic Surgery 2016; 5:156–173. 
  21. Schoenrath F, Laber R, Maralushaj M, Henzi D, Caliskan E, Seifert B, Bettex D, Starck C, Czerny M, Falk V. Survival, Neurologic Injury, and Kidney Function after Surgery for Acute Type A Aortic Dissection. Thorac cardiovasc Surg 2016; 64:100–107. 
  22. Boening A, Karck M, Conzelmann LO, Easo J, Krüger T, Rylski B, Weigang E. German Registry for Acute Aortic Dissection Type A: Structure, Results, and Future Perspectives. Thorac cardiovasc Surg 2016:1–8. 
  23. Hetzer R, Pasic M, Eichstädt H. Chirurgie der Aorta ascendens und des Aortenbogens. Herzmedizin Herzmedizin; 2007; 24:1–7. 
  24. Leshnower BG, Thourani VH, Halkos ME, Sarin EL, Keeling WB, Lamias MJ, Guyton RA, Chen EP. Moderate Versus Deep Hypothermia With Unilateral Selective Antegrade Cerebral Perfusion for Acute Type A Dissection. The Annals of Thoracic Surgery Elsevier; 2015;100: 1563–1569. 
  25. Fukunaga N, Koyama T. Evolution of diagnosis and clinical outcomes in acute aortic dissection: data from the International Registry of Acute Aortic Dissection. J Thorac Dis 2016;8: E625–E627. 
  26. Andersen ND, Benrashid E, Ross AK, Pickett LC, SMITH PK, Daneshmand MA, SCHRODER JN, Gaca JG, Hughes GC. The utility of the aortic dissection team: outcomes and insights after a decade of experience. Annals of Cardiothoracic Surgery 2016;5:194–201. 
  27. Merlo AE, Chauhan D, Pettit C, Hong KN, Saunders CR, Chen C, Russo MJ. Outcomes following emergent open repair for thoracic aortic dissection are improved at higher volume centers in direct admissions and transfers. Journal of Cardiothoracic Surgery Journal of Cardiothoracic Surgery; 2016:1–8. 

Kardiale Notfälle für die Herzchirurgie:Ventrikelruptur, Papillarmuskelabriss, Perikardtamponade
Herbert O. Vetter

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  5. Rankin JS, Hickey MSJ, Smith LR, BeBruijn NP, Sheikh KH, Sabiston DS Jr. Current concepts in the pathogenesis and treatment of ischemis mitral regurgitation. In: Vetter HO, Hetzer R, Schmutzler H (eds) Ischemic mitral incompetence. Steinkopff, Springer 1991:157-178.
  6. Schroeter T, Lehmann S, Misfeld M, Borger M, Subramanian S, Mohr FW, Bakthiary F. Clinical outcome after mitral valve surgery due to ischemic papillary muscle rupture. Ann Thorac Surg 2013; 95:820-824.